Which is the most common drug associated with lichenoid like eruptions?
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Medications commonly reported to trigger a lichenoid drug eruption include: Antihypertensives – ACE inhibitors, beta-blockers, nifedipine, methyldopa. Diuretics – hydrochlorothiazide, frusemide, spironolactone. Non-steroidal anti-inflammatory drugs (NSAIDs)
What causes Lichenoid eruption?
A lichenoid drug eruption is a reaction to a medication. Some of the types of drugs that may trigger this condition include: anticonvulsants, such as carbamazepine (Tegretol) or phenytoin (Dilantin, Phenytek) antihypertensives, including ACE inhibitors, beta-blockers, methyldopa, and nifedipine (Procardia)
What are lichenoid eruptions?
A lichenoid eruption is a skin disease characterized by damage and infiltration between the epidermis and dermis. Examples include lichen planus, lichen sclerosus and lichen nitidus. It can also be associated with abrasion or drug use.
What are lichenoid disorders?
It is a symbiotic fungus/alga characterised by flat-topped organisms. Lichenoid skin disorders got their name from their appearance – also flat topped and often somewhat scaly. They are characterised by a particular type of inflammation found on histology.
What is a drug eruption?
A drug eruption is an adverse skin reaction to a drug. Many medications can cause reactions, especially antimicrobial agents, sulfa drugs, NSAIDs, chemotherapy agents, anticonvulsants, and psychotropic drugs.
How are lichenoid reactions treated?
What is the treatment for an oral lichenoid eruption?
- Potent topical steroids such as clobetasol propionate.
- Other topical treatments such as tacrolimus.
- Oral medications including oral steroids such as prednisone (prednisolone).
What medications trigger lichen planus?
Triggers for lichen planus may include:
- Certain medications. Antimicrobials. Antihistamines (H2-blockers) Antihypertensives/antiarrhythmics such as ACE inhibitors and beta-blockers. Antimalarial drugs.
- Metal dental fillings (oral lichen planus)
- Stress.
- Infection, such as hepatitis C virus infection.
What foods should I avoid with lichen planus?
These sores may burn and be painful. They’ll likely hurt the most when you eat or drink foods that are spicy, salty, acidic (orange juice, tomatoes), or alcoholic. Crispy treats and drinks with caffeine can also cause problems.
Is lichen Nitidus itchy?
Itch. In rare cases, the bumps of lichen nitidus may itch, sometimes intensely. They may appear in a line where there’s a scratch, crease or constant pressure on the skin, such as a fold of skin on the abdomen or the crease of skin on the inside of the elbow or wrist.
What is lichenoid dermatosis?
Lichenoid dermatoses, a group of inflammatory skin conditions with characteristic clinical and histopathologic findings, range from common to rare. Classic lichen planus typically presents as pruritic, polygonal, violaceous flat-topped papules and plaques; many variants in morphology and location also exist.
Which drugs cause drug eruptions?
The most common drugs that may potentially cause drug eruptions include amoxicillin, trimethoprim sulfamethoxazole, ampicillin, penicillin, cephalosporins, quinidine and gentamicin sulfate.
What is bullous eruption?
The term bullous drug eruptions refers to adverse drug reactions that result in fluid-filled blisters or bullae. Blistering can be due to various medications, prescribed or over-the-counter, natural or synthetic. Blistering may be localised and mild, or widespread and severe, even life-threatening.
What are Lichenoid drug eruptions?
Lichenoid drug eruptions are a potential cutaneous side effect of medications including antibiotics, antimalarials, and statins. This drug eruption can mimic features of idiopathic lichen planus in clinical presentation and pathology.
Is atorvastatin a Lichenoid drug eruption?
Lichenoid drug eruptions are a potential cutaneous side effect of medications including antibiotics, antimalarials, and statins. This drug eruption can mimic features of idiopathic lichen planus in clinical presentation and pathology. We describe the case of a 73-year-old man who developed a lichenoid drug eruption secondary to atorvastatin.
Is the Lichenoid drug eruption of hydroxyurea drug-induced dermatomyositis?
The lichenoid drug eruption of hydroxyurea has been reclassified as a drug-induced dermatomyositis. What are the clinical features of a lichenoid drug eruption?
What is a medication-induced eruption of lichen planus?
This medication-induced eruption should be considered when an individual receiving statin treatment develops new lesions akin to lichen planus. The clinical presentation and pathology of lichenoid drug eruptions can mimic those of lichen planus (Table (Table1)1) [15-16,19-20].