What is motif finding in bioinformatics?
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Motif discovery is one of the sequence analysis problems under the application layer and it is one of the significant difficulties in bioinformatics applications. A DNA sequence motif is a subsequence of DNA sequence that is a short similar recurring pattern of nucleotides, and it has many biological functions 1.
What is DNA motif?
A DNA motif is defined as a nucleic acid sequence pattern that has some biological significance such as being DNA binding sites for a regulatory protein, i.e., a transcription factor.
Which tool used for identification of motifs?
Which of the following tools is used for the identification of motifs? Sol: (b) COPIA.
What can you do with a DNA sequence in bioinformatics?
DNA sequencing is used to determine the sequence of individual genes, full chromosomes or entire genomes of an organism. DNA sequencing has also become the most efficient way to sequence RNA or proteins.
What is a motif molecular biology?
• Motif is a region (a subsequence) of protein. or DNA sequence that has a specific. structure.
What is a motif function?
Specific sequence motifs usually mediate a common function, such as protein-binding or targeting to a particular subcellular location, in a variety of proteins. Due to their short length and high level of sequence variability most motifs cannot be reliably predicted by computational means.
What is motif in molecular biology?
A recurring pattern of protein folding, e.g. a homeobox, a zinc finger.
What is an example of a motif?
A motif is a recurring idea or concept throughout a text. A symbol is an object that represents something it is not. A common example is that a heart is a symbol for love. A writer may use a symbol to reinforce motif.
What is DNA in bioinformatics?
Bioinformatics Bioinformatics is a subdiscipline of biology and computer science concerned with the acquisition, storage, analysis, and dissemination of biological data, most often DNA and amino acid sequences.
What do you mean by bioinformatics?
Bioinformatics is defined as the application of tools of computation and analysis to the capture and interpretation of biological data. It is an interdisciplinary field, which harnesses computer science, mathematics, physics, and biology (fig 1).
What is a motif in immunology?
An immunoreceptor tyrosine-based activation motif (ITAM) is a conserved sequence of four amino acids that is repeated twice in the cytoplasmic tails of non-catalytic tyrosine-phosphorylated receptors, cell-surface proteins found mainly on immune cells.
What is motif in biology?
Motif A short (usually not more than 20 amino acids) conserved sequence of biological significance. Motif are of two types (1) Sequence motifs and (2) structure motifs. Motif discovery is the problem of finding recurring patterns in biological data. Patterns can be sequential, mainly when discovered in DNA sequences.
What is motif discovery?
Motif discovery is the problem of finding recurring patterns in biological data. Patterns can be sequential, mainly when discovered in DNA sequences. They can also be structural (e.g. when discovering RNA motifs).
How can I analyze a protein sequence for motifs?
1. The program PROSITE analyzes a protein sequence for these known motifs and gives a description of each. This is useful when analyzing the sequence of a new protein to try to gain clues to its function.
What is the significance of sequence motifs?
Sequence motifs A sequence motif is a nucleotide or amino-acid sequence pattern that is widespread and has, or is conjectured to have, a biological significance. A protein sequence motif is an amino-acid sequence pattern found in similar proteins; change of a motif changes the corresponding biological function.