What is cystic medial necrosis?
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Cystic medial necrosis (CMN) is a disorder of large arteries, in particular the aorta, characterized by an accumulation of basophilic ground substance in the media with cyst-like lesions.
What causes cystic medial degeneration?
Cystic medial necrosis (CMN) is a disease of large arteries, especially the aorta, caused by collagen linking defects leading to deposition of basophilic ground substance in the media, creating cyst-like lesions that weaken the artery wall.
What is the possible consequence of cystic medial degeneration?
Cystic medial necrosis (CMN) or degeneration is found in surgical specimens of aortic dissection, and tends to be associated with higher risks of various aortic complications including aortic dissection and dilatation [1,2,3].
What cells are dying in cystic medial necrosis?
Thoracic aortic aneurysms and dissections are primarily associated with a characteristic histologic appearance known as “medial necrosis” or “Erdheim cystic medial necrosis” which is characterized by degeneration and fragmentation of elastic fibers, loss of smooth muscle cells, and accumulation of basophilic ground …
Is cystic medial necrosis genetic?
Cystic medial necrosis is an autosomal dominant disorder of large arteries.
Can syphilis cause aneurysm?
If the disease progresses, syphilitic aortitis leads to an aortic aneurysm. Overall, tertiary syphilis is a rare cause of aortic aneurysms.
What is the opposite of Marfan syndrome?
Loeys-Dietz syndrome is a connective tissue disorder that was first described in 2005.
What is cystic medial necrosis (CMN)?
Cystic medial necrosis (CMN) is a disorder of large arteries, in particular the aorta, characterized by an accumulation of basophilic ground substance in the media with cyst-like lesions. CMN is known to occur in certain connective tissue diseases such as Marfan syndrome, Ehlers-Danlos syndrome, and …
Where can I find journal articles about cystic medial necrosis of aorta?
PubMed is a searchable database of medical literature and lists journal articles that discuss Cystic medial necrosis of aorta. Click on the link to view a sample search on this topic.
What are the diagnostic categories for cystic MR imaging lesions?
For didactic purposes, lesions with a cystic MR imaging appearance may be classified into one of the following general diagnostic categories: truly cystic (benign) lesions, benign cystlike solid or partly solid lesions, and malignant (and intermediate-grade) solid lesions ( Table 1 ).
What causes cystic necrotic lymph nodes?
Differential diagnosis of cystic necrotic nodes Necrotic lymph node Necrotic lymphadenopathy Cystic necrotic nodes URL of Article Cystic or necrotic appearing lymph nodes can be caused by a number of infectious, inflammatory or malignant conditions: