How long has alendronate been on the market?
Fosamax (alendronate sodium) is a prescription drug used to treat and prevent osteoporosis in adults. It was first introduced to the U.S. market in 1995 by the drug manufacturer Merck.
Who discovered Fosamax?
Discovery and development of alendronate. Alendronate is an alkyl-amino bisphosphonate, closely related to pamidronate and neridronate which have also been used clinically (Fig. 1). Its synthesis was first reported by the Russian chemists, Kabachnik and Vel’tishchev, in 1974.
When was alendronic acid first used?
Alendronic acid was first described in 1978 and approved for medical use in the United States in 1995. It is available as a generic medication. In 2019, it was the 96th most commonly prescribed medication in the United States, with more than 7 million prescriptions.
Is alendronate the same as alendronic acid?
Alendronic acid Brand names: Fosamax, Binosto, alendronate sodium, alendronate.
Is there an alternative to Fosamax?
Boniva is the brand name for the generic drug ibandronate. Like Fosamax, Boniva is also a bisphosphonate. It is FDA-approved to prevent and treat postmenopausal osteoporosis.
What is El alendronato?
El alendronato pertenece a una clase de medicamentos llamados bifosfonatos. Actúa previniendo la degradación de los huesos y aumentando su densidad (grosor). ¿Cómo se debe usar este medicamento? La presentación del alendronato es en forma de tabletas y de solución (líquido) para administrarse por vía oral.
Is alendronate a bisphosphonate?
Alendronate is also used to treat Paget’s disease of bone (a condition in which the bones are soft and weak and may be deformed, painful, or easily broken). Alendronate is in a class of medications called bisphosphonates.
What is alendronate sodium used for?
Alendronic acid (INN) or alendronate sodium, sold in the U.S. under the trade name Fosamax among others, is a bisphosphonate drug used for osteoporosis, osteogenesis imperfecta, and several other bone diseases.
How effective is the alendronato for osteoporosis?
El alendronato controla la osteoporosis y la enfermedad ósea de Paget, pero no las cura. Puede tomar 3 meses o más antes que su nivel de colesterol baje significativamente. El alendronato ayuda a tratar y prevenir la osteoporosis únicamente si se toma con regularidad.