What is metastatic disease?
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Cancer that spreads from where it started to a distant part of the body is called metastatic cancer. For many types of cancer, it is also called stage IV (4) cancer. The process by which cancer cells spread to other parts of the body is called metastasis.
What are the 3 stages of metastasis?
Step 1: invasion and migration.

What is the survival rate for metastatic adenocarcinoma?
The 5-year survival rate for metastatic NSCLC is about 7%. If the cancer only spreads to nearby tissue, the rate improves to 35%. People with localized lung cancer, which has not spread at all, have a 63% survival rate.
What does metastatic mean in cancer?
Metastasis. In metastasis, cancer cells break away from where they first formed (primary cancer), travel through the blood or lymph system, and form new tumors (metastatic tumors) in other parts of the body. The metastatic tumor is the same type of cancer as the primary tumor.
Does metastatic mean terminal?
While metastatic breast cancer is terminal and cannot be cured, because of improved treatments more women are living longer than ever with it. Even so, a lack of information and many misconceptions about this diagnosis persist.

Can metastasis be cured?
In some situations, metastatic cancer can be cured, but most commonly, treatment does not cure the cancer. But doctors can treat it to slow its growth and reduce symptoms. It is possible to live for many months or years with certain types of cancer, even after the development of metastatic disease.
How does metastasis start?
Metastases most commonly develop when cancer cells break away from the main tumor and enter the bloodstream or lymphatic system. These systems carry fluids around the body.
How does metastasis cause death?
If a metastasis lands near or inside these structures, then it may simply block, squeeze, or crush these parts in a way that can be devastating. For example, a metastatic tumor may block an airway or press on the part of the brain that controls breathing.
Is metastatic cancer always fatal?
That’s because cancer that has spread from where it originated in the body to other organs is responsible for most deaths from the disease. But in 1995, two cancer researchers put forth a controversial concept: There is a state of cancer metastasis that isn’t necessarily fatal.
Does metastasis mean death?
I. Metastasis is the general term used to describe the spread of cancer cells from the primary tumor to surrounding tissues and to distant organs and is the primary cause of cancer morbidity and mortality. It is estimated that metastasis is responsible for about 90% of cancer deaths.
Are metastatic cancers curable?
What is metastasis?
Metastasis is the spread of cancer cells to new areas of the body, often by way of the lymph system or bloodstream. A metastatic cancer, or metastatic tumor, is one that has spread from the primary site of origin, or where it started, into different areas of the body.
Why is metastatic cancer so serious?
Metastatic Cancer 1 The main reason that cancer is so serious is its ability to spread in… 2 How Cancer Spreads. During metastasis, cancer cells spread from the place in… 3 Where Cancer Spreads. Cancer can spread to most any part of the body,… 4 Symptoms of Metastatic Cancer. Metastatic cancer does not always cause symptoms.
What is metastatic bone disease?
Metastatic bone disease (MBD) results from the spread of a primary cancer to bone and represents the most common form of bone cancer.
What is locally advanced metastatic cancer?
Diagnosing metastatic cancer Cancer that has spread from the primary, or original, site to other places in the body is generally classified as advanced cancer. When the cancer has spread only to nearby tissues or lymph nodes, it is called locally advanced cancer.