What is the hyperdynamic phase of septic shock?
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When intravascular volume is augmented, the cardiac output usually is elevated (hyperdynamic phase of sepsis and shock). Although cardiac output is elevated, the performance of the heart, reflected by stroke work as calculated from stroke volume and blood pressure, is usually depressed.
What type of shock is associated with hyperdynamic cardiac output?
Types of shock It can be divided into the following four categories: Distributive shock (vasodilation), which is a hyperdynamic process.
What are the key signs and symptoms of septic shock?
Symptoms of septic shock include:
- low blood pressure (hypotension) that makes you feel dizzy when you stand up.
- a change in your mental state, such as confusion or disorientation.
- diarrhoea.
- nausea and vomiting.
- cold, clammy and pale skin.
What is a hyperdynamic pulse?
Hyperdynamic individuals were defined as individuals who had the uppermost 25% of both pulse rate and pulse pressure distributions. Hypodynamic individuals were defined as individuals who had the lowest 25% of both pulse rate and pulse pressure distribution.
Why is SVR high in septic shock?
In the peripheral circulation, a reduction in total peripheral vascular resistance (the ‘systemic vascular resistance’ or SVR) is the norm in sepsis,8 and it is the reflex response to the resulting hypertension that causes the increased cardiac output seen in the ‘classic’ picture of septic shock.
What is the hypodynamic state of septic shock?
These substances induce a marked capillary permeability and a third space loss, leading to hypovolemia. This is the hypodynamic state of septic shock, which is characterized by decreased cardiac output and increased peripheral resistance. Diagnosis should be established in the hyperdynamic state of septic shock.
What is the first phase of septic shock?
Warm shock-the first phase. Septic shock can be broken down into two different types of shock: warm (or hyperdynamic) shock and cold (or hypodynamic) shock. Warm shock characterized by high cardiac output and low peripheral vascular resistance occurs first. Vasodilation from the effects of histamine, bradykinins, serotonin,…
What is the difference between distributive shock and septic shock?
Although septic shock may also be classified as distributive shock, shock can occur in both a volume-depleted and a hyperdynamic phase. Sepsis is the only shock state that changes from a volume-depleted, low blood flow state to a high flow, hyperdynamic state as the patient’s condition worsens.
What is the pathophysiology of sepsis/septic shock?
Pathophysiology Sepsis is a clinical state that falls along a continuum of pathophysiologic states, starting with a systemic inflammatory response syndrome (SIRS) and ending in multiorgan dysfunction syndrome (MODS) before death. The earliest signs of inflammation are heralded by the following: