What if only dengue IgG is positive?
Table of Contents
IgG as a sero-marker of Dengue infection. If the IgG is positive but the IgM is low or negative, then it is likely that the patient had an infection sometime in the past. Presence of IgG alone (absence of NS1 Ag and/or IgM), does not indicate active dengue infection.
How long is dengue IgG positive?
In secondary dengue infections, IgG titers rise to extremely high levels (much higher than in primary infections) from the day 7 of fever to the next two weeks (9, 11). Anti-Dengue IgG antibodies persist for a long time even up to years (3, 12).
How do you read dengue test results?
Interpretation of results
- A positive NS1 test result confirms dengue virus infection without providing serotype information.
- A negative NS1 test result does not rule out infection. People with negative NS1 results should be tested for the presence of dengue IgM antibodies to determine possible recent dengue exposure.
Which of the antibody that provides early diagnosis of dengue and the virus which causes dengue is called?
Immunoglobulin M (IgM) This test looks for IgM (antibodies) in the blood, which appear in the early course of the disease (acute infection). The test can also help to differentiate between primary (first time infection) and secondary (second time infection with any of the dengue virus) infection.
How is dengue IgG treated?
There is no specific medicine to treat dengue infection. If you think you may have dengue fever, you should use pain relievers with acetaminophen and avoid medicines with aspirin, which could worsen bleeding. You should also rest, drink plenty of fluids, and see your doctor.
What if dengue IgG is positive and IgM negative?
If the IgG is positive but the IgM is low or negative, then it is likely that the person had an infection sometime in the past….
IgM Result | IgG Result | Possible Interpretation |
---|---|---|
Positive | Negative | Current infection |
Positive | Positive | Current infection |
When will dengue test be positive?
Dengue virus-specific IgM and neutralizing antibodies typically develop toward the end of the first week of illness. IgM levels are variable, but generally are positive starting 4-5 days after onset of symptoms and continuing for approximately 12 weeks post symptom onset, but may persist longer.
What is the normal range of IgG?
Reference range/units Normal Ranges Adult: IgG 6.0 – 16.0g/L. IgA 0.8 – 3.0g/L. IgM 0.4 – 2.5g/L.