Which insulins is most appropriate for reducing post prandial blood glucose?
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Basal-bolus and biphasic insulin regimens achieve good PPG control, even in patients unable to reach glycemic targets with other treatments.
How do you manage postprandial hyperglycemia?
Therapies such as mealtime insulin, thiazolidinediones (TZDs), DPP-4 inhibitors, glucagon-like peptide-1 (GLP-1) receptor agonists, and meglitinides (or glinides) provide exogenous insulin, stimulate endogenous insulin, increase insulin secretion, and/or suppress postprandial glucagon, thus improving PPG levels (1,7–11 …
What is prandial insulin therapy?
Basal-prandial insulin therapy is a physiologic approach to insulin delivery that utilizes multiple daily injections to cover both basal (ie, overnight fasting and between-meal) and prandial (ie, glucose excursions above basal at mealtime) insulin needs.
Why is postprandial glucose important?
PPG plays a critical role in determining overall glycemic control, particularly in patients who are close to their glycemic goals. Data also indicate that postprandial hyperglycemia may have a greater effect on the development of cardiovascular complications compared with elevated fasting plasma glucose.
How can I lower my PPG?
Therefore, replacing refined carbohydrates and added sugar with grains, legumes, vegetables, and fruits that are rich in dietary fiber may represent an efficient strategy to reduce PPG. Another potential approach is to alter the sequence, or order of consumption of macronutrients during a meal.
What is postprandial hypoglycemia?
Reactive hypoglycemia (postprandial hypoglycemia) refers to low blood sugar that occurs after a meal — usually within four hours after eating.
What is the difference between basal and prandial insulin?
Basal insulin helps keep blood sugars at a consistent level when you are not eating – but it is not enough to cover glucose spikes after meals. Prandial insulins, on the other hand, are taken at mealtime and act rapidly in the body, serving to manage the elevation of glucose levels following meals.
What is prandial insulin example?
Various prandial insulins, including regular human insulin, aspart, glulisine, lispro and fast-acting insulin aspart (FIAsp), are used as part of basal plus, basal bolus, or prandial alone regimens.
What is normal postprandial glucose?
Normal results for the two-hour postprandial test based on age are: For those who don’t have diabetes: less than 140 mg/dL. For those who have diabetes: less than 180 mg/dL.
Can postprandial be lower than fasting?
Postprandial Blood Glucose can be less than Fasting Blood Glucose and this is not a Laboratory Error.