How does air pollution cause atherosclerosis?
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A main suggested mechanism for how air pollution affects the cardiovascular system is that inhaled air pollution causes oxidative stress and systemic inflammation, accelerating the development of atherosclerosis, which in the long term leads to increased risks of clinical cardiovascular events such as myocardial …
Does pollution cause atherosclerosis?
Using the air quality and medical data collected, researchers determined that there was a direct link between air pollution exposure and plaque buildup: healthy individuals exposed to air particle pollution over the long term had accelerated cases of atherosclerosis—to the extent that some participants’ risk for heart …
How does particulate matter cause cardiovascular disease?
In vivo as well as in vitro studies demonstrated that PM particulates can induce pro-thrombotic effects by producing inflammatory mediators in the lungs and releasing into the blood circulation or directly translocation of small particulates from lung to the circulation.
What are the symptoms of particulate matter?
What are the symptoms of particle exposure? Even if you are healthy you may experience temporary symptoms such as irritation of the eyes, nose, and throat, coughing, phlegm, chest tightness, and shortness of breath when particulate conditions are poor.
How does air pollution affect cerebrovascular disease?
Short-term exposure to air pollution increases the risk of intracerebral haemorrhage but not the risk of haemorrhagic stroke overall. Long-term exposure seems to increase the risk of haemorrhagic stroke, but few studies have focused specifically on intracerebral haemorrhage.
How are these harmful particulate related to cardiovascular diseases?
Cardiovascular disease mortality: Fine particle pollution exposure is a risk factor for cardiovascular disease mortality via mechanisms that likely include pulmonary and systemic inflammation, accelerated atherosclerosis, and altered cardiac autonomic function (Dockery et al., 1993).
What are the effects of particulate matter on humans?
Exposure to fine particles can cause short-term health effects such as eye, nose, throat and lung irritation, coughing, sneezing, runny nose and shortness of breath. Exposure to fine particles can also affect lung function and worsen medical conditions such as asthma and heart disease.
Does air pollution particulate matter exposure affect atherosclerosis progression in rabbits?
We sought to determine the effect of exposure to air pollution particulate matter <10 μm (PM 10) on the progression of atherosclerosis in rabbits. Epidemiologic studies have associated exposure to ambient PM 10 with increased cardiovascular morbidity and mortality.
Does particulate air pollution induce progression of atherosclerosis?
Particulate air pollution induces progression of atherosclerosis. J Am Coll Cardiol. 2002;39:935–942. doi: 10.1016/S0735-1097(02)01715-1. [PubMed] [CrossRef] [Google Scholar] Stary HC, Chandler AB, Dinsmore RE, Fuster V, Glagov S, Insull W, Jr, Rosenfeld ME, Schwartz CJ, Wagner WD, Wissler RW.
What are the health effects of air pollution?
Air Pollution has been associated with significant adverse health effects leading to increased morbidity and mortality. Cumulative epidemiological and experimental data have shown that exposure to air pollutants lead to increased cardiovascular ischemic events and enhanced atherosclerosis.
How does particle pollution affect people with heart disease?
If you have heart disease, breathing in particle pollution can cause serious problems like a heart attack. Symptoms include: If you have any of these signs, contact your doctor. Be sure to let your doctor know if the symptoms get worse or last longer than usual.