What is the stratum granulosum composed of?
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Stratum granulosum, 3-5 cell layers, contains diamond shaped cells with keratohyalin granules and lamellar granules. Keratohyalin granules contain keratin precursors that eventually aggregate, crosslink, and form bundles.
What are the grains in the stratum granulosum?
Keratinocytes migrating from the underlying stratum spinosum become known as granular cells in this layer. These cells contain keratohyalin granules, which are filled with histidine- and cysteine-rich proteins that appear to bind the keratin filaments together.

What is specific about stratum granulosum?
The granule cell layer (stratum granulosum) is the next layer (3-5 layers of cells). As the cells move up into this layer, they start to lose their nuclei and cytoplasmic organelles, and turn into the keratinised squames of the next layer. The granules contain a lipid rich secretion, which acts as a water sealant.
What does the stratum granulosum contain quizlet?
The stratum Granulosum consists of 3-5 layers of flattened keratinocytes. What are these cells going through? Apoptosis, Programmed cell death.
How is keratin formed in the stratum spinosum and stratum granulosum?
As the stratum basale continues to produce new cells, the keratinocytes of the stratum spinosum are pushed into the stratum granulosum. The cells become flatter, their cell membranes thicken, and they generate large amounts of the proteins keratin and keratohyalin.

What is the main function of the stratum spinosum?
The main function of the stratum spinosum is to allow keratinocytes (cells that produce keratin) to mature.
What happens in stratum spinosum?
The stratum spinosum helps make your skin flexible and strong. Between the stratum spinosum layer and the stratum lucidum layer. Keratinocytes have granules within them, and in this layer they’re visible under a microscope.
What is the stratum corneum quizlet?
Stratum Corneum. The outermost layer of the epidermis composed of keratinized cells. They are constantly sloughed off and replaced by underlying cells moving to the surface. Keratin.
What part of the skin provides a protective cushion and energy storage for the body?
Subcutaneous adipose (fat) tissue located beneath the dermis; a protective cushion and energy storage for the body. Also called derma, corium, cutis, or true skin, support lay of connective tissue, collagen, and elastin below the epidermis.
What does the stratum spinosum contain?
Stratum spinosum, 8-10 cell layers, also known as the prickle cell layer contains irregular, polyhedral cells with cytoplasmic processes, sometimes called “spines”, that extend outward and contact neighboring cells by desmosomes. Dendritic cells can be found in this layer.
What happens to keratinocytes in the stratum granulosum?
The keratinocytes produce a lot of keratin in this layer—they become filled with keratin. This process is known as keratinization. The keratinocytes become flatter, more brittle, and lose their nuclei in the stratum granulosum as well.
Does stratum spinosum produce keratinocytes?
The stratum spinosum is composed of eight to 10 layers of keratinocytes, formed as a result of cell division in the stratum basale (Figure 4).
What is the main function of the stratum germinativum?
What is the main function of the stratum Germinativum? The stratum germinatum (SG) provides the germinal cells necessary for the regeneration of the layers of the epidermis. These germinal cells are separated from the dermis by a thin layer of basement membrane.
What is the function of the stratum spinosum layer?
– dehydration – toxins – bacteria
Which skin layer holds layers together?
Melanocytes that produce pigment (melanin)
What is the stratum germinativum made up of?
What is the stratum Germinativum made up of? keratinocytes. What are the epidermal ridges? Unlike the epidermis, which was epithelial tissue, the dermis is a layer of connective tissue. It has cells in a matrix (like all connective tissue). These ridges cause ridges in the overlying epidermis, called epidermal ridges.