What is Osteofibrous dysplasia?

What is Osteofibrous dysplasia?

Osteofibrous dysplasia is a noncancerous tumor that typically develops during childhood. It does not spread to other parts of the body and many cases are treated conservatively with careful observation over time. An adamantinoma is a cancerous tumor that is capable of spreading and requires surgery to remove.

Does fibrous dysplasia enhance on MRI?

MRI is not particularly useful in differentiating fibrous dysplasia from other entities as there is marked variability in the appearance of the bone lesions, and they can often resemble a tumor or more aggressive lesions.

How do you diagnose fibrous dysplasia?

The primary tool for diagnosis of fibrous dysplasia is an X-ray. While bone appears solid in an X-ray, a fibrous dysplasia lesion has a relative distinct appearance often described as “ground glass.” The condition may be diagnosed, therefore, even in a person with no symptoms who is getting an X-ray for other reasons.

How can you differentiate between fibrous dysplasia and ossifying fibroma?

in fibrous dysplasia and its deficiency in ossifying fibroma suggests that the calcified material in fibrous dysplasia is more similar to normal bone than that in ossifying fibroma. This marked differ- ence may indicate differences in bone formation and osteoblast differentiation between the two lesions.

Is Osteofibrous dysplasia genetic?

Although fibrous dysplasia is a genetic disorder, it’s caused by a gene mutation that’s not passed from parent to child. There’s no cure for the disorder. Treatment, which may include surgery, focuses on relieving pain and repairing or stabilizing bones.

What are the symptoms of fibrous dysplasia?

What are the symptoms of fibrous dysplasia?

• A waddling walk.
• Bone deformity.
• Bone fractures.
• Bone pain (which happens when the fibrous tissue expands in the bone)
• Scoliosis (a sideways curve of the spine)

Is fibrous dysplasia fatal?

Is fibrous dysplasia aggressive?

Although fibrous dysplasia (FD) is a benign fibro-osseous lesion, locally aggressive behaviour has rarely been described but is poorly characterised.

Is fibrous dysplasia treatable?

Is fibrous dysplasia progressive?

Fibrous dysplasia is a chronic disorder and is often progressive. Although the lesions may stabilize and stop growing, they do not disappear. Individual lesions may progress more rapidly in the polyostotic form of the condition and in growing children.

What causes juvenile ossifying fibroma?

It has been thought that JOF arises as a result of differentiation of multipotential precursor cells or mesenchymal cells of the periodontal ligament to form cementum, osteoid or fibrous tissue combination. Fibro-osseous lesions involving craniofacial skeleton display a variety of clinical behavior.

Is fibrous dysplasia a disability?

Fibrous dysplasia is a condition where primitive bone cells proliferate inside the bone, weakening its structure and causing pain and disability.

INTRODUCTION Osteofibrous dysplasia, also termed ossifying fibroma of long bones, is a rare benign fibro-osseous lesion that has a strong predilection for an involvement of the tibia in the early childhood. The biologic behavior of osteofibrous dysplasia is reportedly diverse, ranging from non-progressive to recurrent and more aggressive lesions.

What are Osteofibrous dysplasia and adamantinoma?

Osteofibrous dysplasia (OFD) and adamantinoma are rare bone tumors that are most often found in the tibia (shinbone). Osteofibrous dysplasia is a noncancerous tumor that typically develops during childhood.

What is the role of MRI in the evaluation of Osteofibrous dysplasia?

MRI is helpful in evaluation of suspected osteofibrous dysplasia, particularly to evaluate the extent of intramedullary involvement. Complete medullary cavity involvement is more suggestive of adamantinoma. T1C+: diffuse and intense enhancement. Surgery is reserved for lesions that are large or demonstrate aggressive behavior.

What happens if you have a tumor on your tibia?

When the tumor develops in the tibia, the lower leg may have deformed appearance due to curving (bowing) of the bone. Before a physical examination, your doctor will talk with you about your general health and your symptoms in order to get a good history of the problem.